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Expression and prognostic value of transcription factor PROX1 in colorectal cancer

BACKGROUND: PROX1 is a specific target of the β-catenin/TCF pathway in the intestinal epithelium. It acts as a regulator of progression from a benign to a highly dysplastic phenotype in colorectal tumours. However, the clinical significance of PROX1 expression is not known. METHODS: We studied the p...

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Autores principales: Skog, M, Bono, P, Lundin, M, Lundin, J, Louhimo, J, Linder, N, Petrova, T V, Andersson, L C, Joensuu, H, Alitalo, K, Haglund, C H
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241535/
https://ncbi.nlm.nih.gov/pubmed/21970873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.297
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