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Regulating Immune Response Using Polyvalent Nucleic Acid-Gold Nanoparticle Conjugates

The immune response of macrophage cells to internalized polyvalent nucleic acid-functionalized gold nanoparticles has been studied. This study finds that the innate immune response (as measured by interferon-β levels) to densely functionalized, oligonucleotide-modified nanoparticles is significantly...

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Autori principali: Massich, Matthew D., Giljohann, David A., Seferos, Dwight S., Ludlow, Louise E., Horvath, Curt M., Mirkin, Chad A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241524/
https://ncbi.nlm.nih.gov/pubmed/19810673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900172m
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