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Evaluation of the Synthesis of Sialic Acid-PAMAM Glycodendrimers without the Use of Sugar Protecting Groups, and the Anti-HIV-1 Properties of These Compounds

A study was undertaken to evaluate the feasibility of synthesizing six sialic acid-PAMAM glycodendrimers using unprotected sialic acid in as few as 1-4 steps using two different reaction pathways, and to assess the sulfated derivatives for anti-HIV activity. The syntheses were accomplished through e...

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Detalhes bibliográficos
Main Authors: Clayton, Russell, Hardman, Janee’, LaBranche, Celia C., McReynolds, Katherine D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241508/
https://ncbi.nlm.nih.gov/pubmed/21859137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200331v
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