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Environment-Sensitive Epigenetics and the Heritability of Complex Diseases

Genome-wide association studies have thus far failed to explain the observed heritability of complex human diseases. This is referred to as the “missing heritability” problem. However, these analyses have usually neglected to consider a role for epigenetic variation, which has been associated with m...

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Détails bibliographiques
Auteurs principaux: Furrow, Robert E., Christiansen, Freddy B., Feldman, Marcus W.
Format: Artigo
Langue:Inglês
Publié: Genetics Society of America 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241426/
https://ncbi.nlm.nih.gov/pubmed/21968193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.131912
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