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Environment-Sensitive Epigenetics and the Heritability of Complex Diseases

Genome-wide association studies have thus far failed to explain the observed heritability of complex human diseases. This is referred to as the “missing heritability” problem. However, these analyses have usually neglected to consider a role for epigenetic variation, which has been associated with m...

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Detalhes bibliográficos
Main Authors: Furrow, Robert E., Christiansen, Freddy B., Feldman, Marcus W.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241426/
https://ncbi.nlm.nih.gov/pubmed/21968193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.131912
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