Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures

INTRODUCTION: The aim of this study was to examine the effect of blocking Toll-like receptor 2 (TLR2) in rheumatoid arthritis (RA) synovial cells. METHODS: RA synovial tissue biopsies, obtained under direct visualization at arthroscopy, were established as synovial explant cultures ex vivo or snap f...

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Hlavní autoři: Nic An Ultaigh, Sinéad, Saber, Tajvur P, McCormick, Jennifer, Connolly, Mary, Dellacasagrande, Jerome, Keogh, Brian, McCormack, William, Reilly, Mary, O'Neill, Luke A, McGuirk, Peter, Fearon, Ursula, Veale, Douglas J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241377/
https://ncbi.nlm.nih.gov/pubmed/21345222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3261
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