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Toll-Like Receptor 2 Induced Angiogenesis and Invasion Is Mediated through the Tie2 Signalling Pathway in Rheumatoid Arthritis

BACKGROUND: Angiogenesis is a critical early event in inflammatory arthritis, facilitating leukocyte migration into the synovium resulting in invasion and destruction of articular cartilage and bone. This study investigates the effect of TLR2 on angiogenesis, EC adhesion and invasion using microvasc...

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Bibliografiske detaljer
Main Authors: Saber, Tajvur, Veale, Douglas J., Balogh, Emese, McCormick, Jennifer, NicAnUltaigh, Sinead, Connolly, Mary, Fearon, Ursula
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157402/
https://ncbi.nlm.nih.gov/pubmed/21858161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023540
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