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Toll-Like Receptor 2 Induced Angiogenesis and Invasion Is Mediated through the Tie2 Signalling Pathway in Rheumatoid Arthritis

BACKGROUND: Angiogenesis is a critical early event in inflammatory arthritis, facilitating leukocyte migration into the synovium resulting in invasion and destruction of articular cartilage and bone. This study investigates the effect of TLR2 on angiogenesis, EC adhesion and invasion using microvasc...

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Detalhes bibliográficos
Main Authors: Saber, Tajvur, Veale, Douglas J., Balogh, Emese, McCormick, Jennifer, NicAnUltaigh, Sinead, Connolly, Mary, Fearon, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157402/
https://ncbi.nlm.nih.gov/pubmed/21858161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023540
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