Relationships between biomarkers of cartilage, bone, synovial metabolism and knee pain provide insights into the origins of pain in early knee osteoarthritis

INTRODUCTION: We tested the hypothesis that there exist relationships between the onset of early stage radiographically defined knee osteoarthritis (OA), pain and changes in biomarkers of joint metabolism. METHODS: Using Kellgren-Lawrence (K/L) grading early radiographic knee OA (K/L 2) was detected...

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Detalhes bibliográficos
Main Authors: Ishijima, Muneaki, Watari, Taiji, Naito, Kiyohito, Kaneko, Haruka, Futami, Ippei, Yoshimura-Ishida, Kaori, Tomonaga, Akihito, Yamaguchi, Hideyo, Yamamoto, Tetsuro, Nagaoka, Isao, Kurosawa, Hisashi, Poole, Robin A, Kaneko, Kazuo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241366/
https://ncbi.nlm.nih.gov/pubmed/21320321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3246
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