Mapping sequences in loops of nuclear DNA by their progressive detachment from the nuclear cage.
Nuclear DNA is organised into loops, probably by attachment to a supramolecular structure. We describe a method which enables us to map the position of sequences within a loop relative to the point of attachment. Nuclear DNA is isolated unbroken by lysing HeLa cells in 2M NaCl to release structures...
Guardat en:
| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1980
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| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC324133/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7433096/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/8.13.2895 |
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