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Mapping sequences in loops of nuclear DNA by their progressive detachment from the nuclear cage.

Nuclear DNA is organised into loops, probably by attachment to a supramolecular structure. We describe a method which enables us to map the position of sequences within a loop relative to the point of attachment. Nuclear DNA is isolated unbroken by lysing HeLa cells in 2M NaCl to release structures...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Cook, P R, Brazell, I A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1980
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC324133/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7433096/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/8.13.2895
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