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Plasticity of Prefrontal Attention Circuitry: Upregulated Muscarinic Excitability in Response to Decreased Nicotinic Signaling Following Deletion of α5 or β2 Subunits

Attention depends on cholinergic stimulation of nicotinic and muscarinic acetylcholine receptors in the medial prefrontal cortex. Pyramidal neurons in layer VI of this region express cholinergic receptors of both families and play an important role in attention through their feedback projections to...

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Autori principali: Tian, Michael K., Bailey, Craig D. C., De Biasi, Mariella, Picciotto, Marina R., Lambe, Evelyn K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240894/
https://ncbi.nlm.nih.gov/pubmed/22072695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3600-11.2011
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