Structural Instability Tuning as a Regulatory Mechanism in Protein-Protein Interactions

Protein-protein interactions mediate a vast number of cellular processes. Here we present a regulatory mechanism in protein-protein interactions mediated by finely-tuned structural instability coupled with molecular mimicry. We show that a set of type III secretion (TTS) autoinhibited homodimeric ch...

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Autores principales: Chen, Li, Balabanidou, Vassilia, Remeta, David P., Minetti, Conceição A.S.A., Portaliou, Athina G., Economou, Anastassios, Kalodimos, Charalampos G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240846/
https://ncbi.nlm.nih.gov/pubmed/22152477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.09.022
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