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Tandem SAM Domain Structure of Human Caskin1: A Presynaptic, Self-Assembling Scaffold for CASK

The synaptic scaffolding proteins CASK and Caskin1 are part of the fibrous mesh of proteins that organize the active zones of neural synapses. CASK binds to a region of Caskin1 called the CASK interaction domain (CID). Adjacent to the CID, Caskin1 contains two tandem sterile alpha motif (SAM) domain...

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Autors principals: Stafford, Ryan L., Hinde, Elizabeth, Knight, Mary Jane, Pennella, Mario A., Ear, Jason, Digman, Michelle A., Gratton, Enrico, Bowie, James U.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240820/
https://ncbi.nlm.nih.gov/pubmed/22153505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.09.018
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