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In vivo pair correlation analysis of EGFP intranuclear diffusion reveals DNA-dependent molecular flow

No methods proposed thus far have the capability to measure overall molecular flow in the nucleus of living cells. Here, we apply the pair correlation function analysis (pCF) to measure molecular anisotropic diffusion in the interphase nucleus of live cells. In the pCF method, we cross-correlate flu...

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Detalhes bibliográficos
Main Authors: Hinde, Elizabeth, Cardarelli, Francesco, Digman, Michelle A., Gratton, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944750/
https://ncbi.nlm.nih.gov/pubmed/20823232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006731107
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