MicroRNA-449a Overexpression, Reduced NOTCH1 Signals and Scarce Goblet Cells Characterize the Small Intestine of Celiac Patients

MiRNAs play a relevant role in regulating gene expression in a variety of physiological and pathological conditions including autoimmune disorders. MiRNAs are also important in the differentiation and function of the mouse intestinal epithelium. Our study was aimed to look for miRNA-based modulation...

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Autori principali: Capuano, Marina, Iaffaldano, Laura, Tinto, Nadia, Montanaro, Donatella, Capobianco, Valentina, Izzo, Valentina, Tucci, Francesca, Troncone, Giancarlo, Greco, Luigi, Sacchetti, Lucia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240641/
https://ncbi.nlm.nih.gov/pubmed/22194996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029094
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