MicroRNA-449a Overexpression, Reduced NOTCH1 Signals and Scarce Goblet Cells Characterize the Small Intestine of Celiac Patients

MiRNAs play a relevant role in regulating gene expression in a variety of physiological and pathological conditions including autoimmune disorders. MiRNAs are also important in the differentiation and function of the mouse intestinal epithelium. Our study was aimed to look for miRNA-based modulation...

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Detalhes bibliográficos
Main Authors: Capuano, Marina, Iaffaldano, Laura, Tinto, Nadia, Montanaro, Donatella, Capobianco, Valentina, Izzo, Valentina, Tucci, Francesca, Troncone, Giancarlo, Greco, Luigi, Sacchetti, Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240641/
https://ncbi.nlm.nih.gov/pubmed/22194996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029094
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