Single Cell Analysis Facilitates Staging of Blimp1-Dependent Primordial Germ Cells Derived from Mouse Embryonic Stem Cells

The cell intrinsic programming that regulates mammalian primordial germ cell (PGC) development in the pre-gonadal stage is challenging to investigate. To overcome this we created a transgene-free method for generating PGCs in vitro (iPGCs) from mouse embryonic stem cells (ESCs). Using labeling for S...

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Autors principals: Vincent, John J., Li, Ziwei, Lee, Serena A., Liu, Xian, Etter, Marisabel O., Diaz-Perez, Silvia V., Taylor, Sara K., Gkountela, Sofia, Lindgren, Anne G., Clark, Amander T.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240638/
https://ncbi.nlm.nih.gov/pubmed/22194959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028960
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