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A Dominant Negative Zebrafish Ahr2 Partially Protects Developing Zebrafish from Dioxin Toxicity

The toxicity by 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD) is thought to be caused by activation of the aryl hydrocarbon receptor (AHR). However, our understanding of how AHR activation by TCDD leads to toxic effects is poor. Ideally we would like to manipulate AHR activity in specific tissues and a...

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Detalhes bibliográficos
Main Authors: Lanham, Kevin A., Prasch, Amy L., Weina, Kasia M., Peterson, Richard E., Heideman, Warren
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240621/
https://ncbi.nlm.nih.gov/pubmed/22194803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028020
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