Macrophage-Specific Chemokines Induced via Innate Immunity by Amino Acid Copolymers and Their Role in EAE

The random amino acid copolymer poly(Y,E,A,K)(n) (Copaxone®) is widely used in multiple sclerosis treatment and a second generation copolymer poly(Y,F,A,K)(n) with enhanced efficacy in experimental autoimmune encephalomyelitis in mice has been described. A major mechanism through which copolymers fu...

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Main Authors: Kovalchin, Joseph, Krieger, Jeffrey, Genova, Michelle, Kawamoto, Norio, Augustyniak, Michael, Collins, Kathryn, Bloom, Troy, Masci, Allyson, Hittinger, Tara, Dufour, Ingrid, Strominger, Jack L., Zanelli, Eric
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240613/
https://ncbi.nlm.nih.gov/pubmed/22194778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026274
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