Humanized mice as a model for rheumatoid arthritis

CHAPTER SUMMARY: Genetic susceptibility to rheumatoid arthritis (RA), a common autoimmune disease, is associated with certain HLA-DR4 alleles. Treatments are rarely curative and are often tied to major side effects. We describe the development of a humanized mouse model wherein new, less toxic, vacc...

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Detalhes bibliográficos
Main Authors: Eming, Rüdiger, Visconti, Kevin, Hall, Frances, Sekine, Chiyoko, Kobayashi, Kayta, Chen, Qun, Cope, Andrew, Kanazawa, Satoshi, Peterlin, Matija, Rijnders, Antonius, Boots, Annemieke, Meijerink, Jan, Sønderstrup, Grete
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2002
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240155/
https://ncbi.nlm.nih.gov/pubmed/12110132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar580
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