Aberrant MHC class II expression in mouse joints leads to arthritis with extraarticular manifestations similar to rheumatoid arthritis

Genetic susceptibility to rheumatoid arthritis (RA) is associated with certain MHC class II molecules. To clarify the role of these determinants in RA, we generated the D1CC transgenic mouse that expressed genes involved in antigen processing and presentation by the MHC class II pathway in joints. T...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kanazawa, Satoshi, Ota, Shusuke, Sekine, Chiyoko, Tada, Toyohiro, Otsuka, Takanobu, Okamoto, Takashi, Sønderstrup, Grete, Peterlin, B. Matija
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2006
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1599985/
https://ncbi.nlm.nih.gov/pubmed/16980409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606450103
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg