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Physical mapping of the globin gene deletion in hereditary persistence of foetal haemoglobin (HPFH).

We have mapped the globin gene region in the DNA of two HPFH patients. In a patient homozygous for the G gamma A gamma type of HPFH at least 24 kb of DNA in the globin gene region has been deleted to remove most of the gamma-delta intergenic region and the delta and beta globin genes. The 5' br...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bernards, R, Flavell, R A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1980
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC324014/
https://ncbi.nlm.nih.gov/pubmed/6159595
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