Targeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells

BACKGROUND: Cancer cells have a different metabolic profile compared to normal cells. The Warburg effect (increased aerobic glycolysis) and glutaminolysis (increased mitochondrial activity from glutamine catabolism) are well known hallmarks of cancer and are accompanied by increased lactate producti...

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Autori principali: Sun, Ramon C, Board, Philip G, Blackburn, Anneke C
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240126/
https://ncbi.nlm.nih.gov/pubmed/22093145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-142
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