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Targeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells
BACKGROUND: Cancer cells have a different metabolic profile compared to normal cells. The Warburg effect (increased aerobic glycolysis) and glutaminolysis (increased mitochondrial activity from glutamine catabolism) are well known hallmarks of cancer and are accompanied by increased lactate producti...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3240126/ https://ncbi.nlm.nih.gov/pubmed/22093145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-142 |
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