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Targeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells

BACKGROUND: Cancer cells have a different metabolic profile compared to normal cells. The Warburg effect (increased aerobic glycolysis) and glutaminolysis (increased mitochondrial activity from glutamine catabolism) are well known hallmarks of cancer and are accompanied by increased lactate producti...

詳細記述

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書誌詳細
主要な著者: Sun, Ramon C, Board, Philip G, Blackburn, Anneke C
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240126/
https://ncbi.nlm.nih.gov/pubmed/22093145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-142
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