Constitutive expression of cathepsin K in the human intervertebral disc: new insight into disc extracellular matrix remodeling via cathepsin K and receptor activator of nuclear factor-κB ligand

INTRODUCTION: Cathepsin K is a recently discovered cysteine protease which cleaves the triple helical domains of type I to II collagen. It has been shown to be up-regulated in synovial tissue from osteoarthritic and rheumatoid patients, and is a component in normal and nonarthritic cartilage, where...

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Main Authors: Gruber, Helen E, Ingram, Jane A, Hoelscher, Gretchen L, Zinchenko, Natalia, Norton, H James, Hanley, Edward N
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2011
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239383/
https://ncbi.nlm.nih.gov/pubmed/21880134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3454
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