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Matrix metalloproteinase 28, a novel matrix metalloproteinase, is constitutively expressed in human intervertebral disc tissue and is present in matrix of more degenerated discs

INTRODUCTION: The regulation and elevation in expression of the catabolic matrix metalloproteinases (MMPs) is of high importance in the human intervertebral disc since upregulation of these matrix-degrading enzymes results in matrix destruction associated with disc degeneration. MMP28 (epilysin) is...

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Main Authors: Gruber, Helen E, Ingram, Jane A, Hoelscher, Gretchen L, Zinchenko, Natalia, Norton, H James, Hanley, Edward N
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003526/
https://ncbi.nlm.nih.gov/pubmed/20003223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2876
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