SIRT1 links CIITA deacetylation to MHC II activation

Antigen-dependent stimulation of T cells plays a critical role in adaptive immunity and host defense. Activation of major histocompatibility complex II (MHC II) molecules, dictated by Class II transactivator (CIITA), is considered a pivotal step in this process. The mechanism underlying differential...

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Dades bibliogràfiques
Autors principals: Wu, Xiaoyan, Kong, Xiaocen, Chen, Dewei, Li, He, Zhao, Yuhao, Xia, Minjie, Fang, Mingming, Li, Ping, Fang, Fei, Sun, Lina, Tian, Wenfang, Xu, Huihui, Yang, Yuyu, Qi, Xiaohong, Gao, Yuqi, Sha, Jiahao, Chen, Qi, Xu, Yong
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Gene Regulation, Chromatin and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239213/
https://ncbi.nlm.nih.gov/pubmed/21890893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr651
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