Identification of potentially cytotoxic lesions induced by UVA photoactivation of DNA 4-thiothymidine in human cells

Photochemotherapy—in which a photosensitizing drug is combined with ultraviolet or visible radiation—has proven therapeutic effectiveness. Existing approaches have drawbacks, however, and there is a clinical need to develop alternatives offering improved target cell selectivity. DNA substitution by...

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Main Authors: Reelfs, Olivier, Macpherson, Peter, Ren, Xiaolin, Xu, Yao-Zhong, Karran, Peter, Young, Antony R.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239200/
https://ncbi.nlm.nih.gov/pubmed/21890905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr674
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