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Thiothymidine plus low-dose UVA kills hyperproliferative human skin cells independently of their human papilloma virus status

The thymidine analogue 4-thiothymidine (S(4)TdR) is a photosensitizer for UVA radiation. The UV absorbance spectrum of S(4)TdR and its incorporation into DNA suggests that it might act synergistically with nonlethal doses of UVA to selectively kill hyperproliferative or cancerous skin cells. We show...

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Bibliografische gegevens
Hoofdauteurs: Reelfs, Olivier, Xu, Yao-Zhong, Massey, Andrew, Karran, Peter, Storey, Alan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423463/
https://ncbi.nlm.nih.gov/pubmed/17876046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-0166
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