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Signal-induced Brd4 release from chromatin is essential for its role transition from chromatin targeting to transcriptional regulation
Bromodomain-containing protein Brd4 is shown to persistently associate with chromosomes during mitosis for transmitting epigenetic memory across cell divisions. During interphase, Brd4 also plays a key role in regulating the transcription of signal-inducible genes by recruiting positive transcriptio...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3239188/ https://ncbi.nlm.nih.gov/pubmed/21890894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr698 |
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