Signal-induced Brd4 release from chromatin is essential for its role transition from chromatin targeting to transcriptional regulation

Bromodomain-containing protein Brd4 is shown to persistently associate with chromosomes during mitosis for transmitting epigenetic memory across cell divisions. During interphase, Brd4 also plays a key role in regulating the transcription of signal-inducible genes by recruiting positive transcriptio...

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Detalhes bibliográficos
Main Authors: Ai, Nanping, Hu, Xiangming, Ding, Feng, Yu, Bingfei, Wang, Huiping, Lu, Xiaodong, Zhang, Kai, Li, Yannan, Han, Aidong, Lin, Wen, Liu, Runzhong, Chen, Ruichuan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3239188/
https://ncbi.nlm.nih.gov/pubmed/21890894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr698
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