Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA

DPF3 (BAF45c) is a member of the BAF chromatin remodeling complex. Two isoforms have been described, namely DPF3a and DPF3b. The latter binds to acetylated and methylated lysine residues of histones. Here, we elaborate on the role of DPF3a and describe a novel pathway of cardiac gene transcription l...

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Publicat a:Nucleic Acids Res
Autors principals: Cui, Huanhuan, Schlesinger, Jenny, Schoenhals, Sophia, Tönjes, Martje, Dunkel, Ilona, Meierhofer, David, Cano, Elena, Schulz, Kerstin, Berger, Michael F., Haack, Timm, Abdelilah-Seyfried, Salim, Bulyk, Martha L., Sauer, Sascha, Sperling, Silke R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Gene regulation, Chromatin and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824069/
https://ncbi.nlm.nih.gov/pubmed/26582913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1244
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