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Improved accuracy of supervised CRM discovery with interpolated Markov models and cross-species comparison
Despite recent advances in experimental approaches for identifying transcriptional cis-regulatory modules (CRMs, ‘enhancers’), direct empirical discovery of CRMs for all genes in all cell types and environmental conditions is likely to remain an elusive goal. Effective methods for computational CRM...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3239187/ https://ncbi.nlm.nih.gov/pubmed/21821659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr621 |
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