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A gene deletion ending within a complex array of repeated sequences 3' to the human beta-globin gene cluster.

A DNA fragment containing the deletion junction region from an Indian individual with a type of hereditary persistence of fetal hemoglobin has been cloned. Using a probe isolated from this deletion-spanning clone, we located the 3' breakpoint of the deletion in normal DNA to a region 30 kilobase pai...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Henthorn, P S, Mager, D L, Huisman, T H, Smithies, O
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323917/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2425363/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.14.5194
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