Topoisomerase I identified by scleroderma 70 antisera: enrichment of topoisomerase I at the centromere in mouse mitotic cells before anaphase.

Antibodies derived from scleroderma patients positive for the extractable 70-kDa antigen were shown to react with topoisomerase I. Topoisomerase I was identified by molecular size and by antibody inhibition of the topoisomerase I-specific relaxation of supercoiled plasmid DNA. By using in situ local...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Maul, G G, French, B T, van Venrooij, W J, Jimenez, S A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323907/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3014535/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.14.5145
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