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Mutations affecting the signal sequence alter synthesis and secretion of yeast invertase.

Insertion mutations previously constructed within the proximal region of the yeast invertase signal sequence did not interfere with secretion or glycosylation of the enzyme. We now describe deletion mutations within the same signal sequence. Large deletions truncating the hydrophobic core of the sig...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Perlman, D, Raney, P, Halvorson, H O
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1986
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323884/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3523480/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.14.5033
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