Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog

In mammals, the PGC-1 transcriptional co-activators are key regulators of energy metabolism, including mitochondrial biogenesis and respiration, which have been implicated in numerous pathogenic conditions including neurodegeneration and cardiomyopathy. Here, we show that overexpression of the Droso...

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Autori principali: Rera, Michael, Bahadorani, Sepehr, Cho, Jaehyoung, Koehler, Christopher L., Ulgherait, Matthew, Hur, Jae H., Ansari, William S., Lo, Thomas, Jones, D. Leanne, Walker, David W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3238792/
https://ncbi.nlm.nih.gov/pubmed/22055505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.09.013
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