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Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog
In mammals, the PGC-1 transcriptional co-activators are key regulators of energy metabolism, including mitochondrial biogenesis and respiration, which have been implicated in numerous pathogenic conditions including neurodegeneration and cardiomyopathy. Here, we show that overexpression of the Droso...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3238792/ https://ncbi.nlm.nih.gov/pubmed/22055505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.09.013 |
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