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CX3CR1 deficient mice have decreased Th17 and antigen-specific humoral responses in the collagen induced arthritis (CIA) model

OBJECTIVE: CX3CR1 is a chemokine receptor that uniquely binds to its ligand fractalkine (FKN or CX3CL1) and has been shown to be important in inflammatory arthritis responses largely due to effects on cellular migration. In this study, we tested the hypothesis that genetic deficiency of CX3CR1 would...

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Main Authors: Tarrant, Teresa K., Liu, Peng, Rampersad, Rishi R., Esserman, Denise, Rothlein, Lisa R., Timoshchenko, Roman G, McGinnis, Marcus W., Fitzhugh, David J, Patel, Dhavalkumar D., Fong, Alan M.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3238788/
https://ncbi.nlm.nih.gov/pubmed/22144035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34320
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