Dynamics of the B-to-Z transition in supercoiled DNA.
The sequence (dC-dG)16, inserted into the polylinker of plasmid pUC8, adopts a left-handed Z-DNA conformation at "natural" supercoil density. The radioactively labeled monoclonal antibody Z-D11, which has a very high affinity for this DNA conformation, provides a convenient sensitive tool to measure...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1986
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323873/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3460079/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.14.4983 |
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