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Dynamics of the B-to-Z transition in supercoiled DNA.

The sequence (dC-dG)16, inserted into the polylinker of plasmid pUC8, adopts a left-handed Z-DNA conformation at "natural" supercoil density. The radioactively labeled monoclonal antibody Z-D11, which has a very high affinity for this DNA conformation, provides a convenient sensitive tool to measure...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autor Principal: Pohl, F M
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1986
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323873/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3460079/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.14.4983
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