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Recombinant interferon alpha can induce rearrangement of T-cell antigen receptor alpha-chain genes and maturation to cytotoxicity in T-lymphocyte clones in vitro.

T-cell receptor genes are found in the germ-line configuration as well as in rearranged forms, as detected in T lymphocytes by different patterns in Southern blot analysis. We have recently shown that cytotoxic T-lymphocyte (CTL) "precursor" clones, in which rearrangements are not detected...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Chen, L K, Mathieu-Mahul, D, Bach, F H, Dausset, J, Bensussan, A, Sasportes, M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1986
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC323848/
https://ncbi.nlm.nih.gov/pubmed/3487784
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