Atrial natriuretic peptide inhibits renin release from juxtaglomerular cells by a cGMP-mediated process.

We have examined the effect of a synthetic analogue of human alpha-atrial natriuretic peptide (ANP), APII, on renin release in cultured renal juxtaglomerular cells (JGA cells). Using cell cultures containing 80-90% renal juxtaglomerular cells, we found that ANP (10(-13)-10(-9) M) strongly inhibited...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kurtz, A, Della Bruna, R, Pfeilschifter, J, Taugner, R, Bauer, C
Format: Artigo
Langue:Inglês
Publié: 1986
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC323823/
https://ncbi.nlm.nih.gov/pubmed/3014509
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