Atrial natriuretic peptide inhibits renin release from juxtaglomerular cells by a cGMP-mediated process.
We have examined the effect of a synthetic analogue of human alpha-atrial natriuretic peptide (ANP), APII, on renin release in cultured renal juxtaglomerular cells (JGA cells). Using cell cultures containing 80-90% renal juxtaglomerular cells, we found that ANP (10(-13)-10(-9) M) strongly inhibited...
Spremljeno u:
| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1986
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323823/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3014509/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.13.4769 |
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