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Atrial natriuretic peptide inhibits renin release from juxtaglomerular cells by a cGMP-mediated process.

We have examined the effect of a synthetic analogue of human alpha-atrial natriuretic peptide (ANP), APII, on renin release in cultured renal juxtaglomerular cells (JGA cells). Using cell cultures containing 80-90% renal juxtaglomerular cells, we found that ANP (10(-13)-10(-9) M) strongly inhibited...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Kurtz, A, Della Bruna, R, Pfeilschifter, J, Taugner, R, Bauer, C
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1986
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323823/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3014509/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.13.4769
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