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Epigenetic Regulation of Motor Neuron Cell Death through DNA Methylation
DNA methylation is an epigenetic mechanism for gene silencing engaged by DNA methyltransferase (Dnmt)-catalyzed methyl group transfer to cytosine residues in gene-regulatory regions. It is unknown whether aberrant DNA methylation can cause neurodegeneration. We tested the hypothesis that Dnmts can m...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Society for Neuroscience
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3238138/ https://ncbi.nlm.nih.gov/pubmed/22090490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1639-11.2011 |
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