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Isolation of a Drosophila genomic sequence homologous to the kinase domain of the human insulin receptor and detection of the phosphorylated Drosophila receptor with an anti-peptide antibody.

A Drosophila genomic fragment has been isolated with a deduced amino acid sequence that is strikingly homologous to that of the kinase domain of the human insulin receptor. The Drosophila DNA hybridizes with an 11-kilobase mRNA that is most prominent in 8- to 12-hr embryos. An anti-peptide antibody...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Petruzzelli, L, Herrera, R, Arenas-Garcia, R, Fernandez, R, Birnbaum, M J, Rosen, O M
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1986
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323811/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3014506/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.13.4710
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