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Alzheimer's Therapeutics: Translation of Preclinical Science to Clinical Drug Development

Over the past three decades, significant progress has been made in understanding the neurobiology of Alzheimer's disease. In recent years, the first attempts to implement novel mechanism-based treatments brought rather disappointing results, with low, if any, drug efficacy and significant side...

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Detalhes bibliográficos
Main Authors: Savonenko, Alena V, Melnikova, Tatiana, Hiatt, Andrew, Li, Tong, Worley, Paul F, Troncoso, Juan C, Wong, Phil C, Price, Don L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3238084/
https://ncbi.nlm.nih.gov/pubmed/21937983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.211
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