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Alzheimer's Therapeutics: Translation of Preclinical Science to Clinical Drug Development

Over the past three decades, significant progress has been made in understanding the neurobiology of Alzheimer's disease. In recent years, the first attempts to implement novel mechanism-based treatments brought rather disappointing results, with low, if any, drug efficacy and significant side...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Savonenko, Alena V, Melnikova, Tatiana, Hiatt, Andrew, Li, Tong, Worley, Paul F, Troncoso, Juan C, Wong, Phil C, Price, Don L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3238084/
https://ncbi.nlm.nih.gov/pubmed/21937983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.211
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