Mitochondrial abnormality in sensory, but not motor, axons in paclitaxel-evoked painful peripheral neuropathy in the rat

The dose-limiting side effect of the anti-neoplastic agent, paclitaxel, is a chronic distal symmetrical peripheral neuropathy that produces sensory dysfunction (hypoesthesia and neuropathic pain) but little or no distal motor dysfunction. Similar peripheral neuropathies are seen with chemotherapeuti...

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Bibliographic Details
Main Authors: Xiao, Wen Hua, Zheng, Huaien, Zheng, Felix Y., Nuydens, Rony, Meert, Theo F., Bennett, Gary J.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237950/
https://ncbi.nlm.nih.gov/pubmed/22037390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2011.10.010
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