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Prevention of paclitaxel-evoked painful peripheral neuropathy by acetyl-L-carnitine: Effects on axonal mitochondria, sensory nerve fiber terminal arbors, and cutaneous Langerhans cells

Prophylactic treatment with acetyl-L-carnitine (ALCAR) prevents the neuropathic pain syndrome that is evoked by the chemotherapeutic agent, paclitaxel. The paclitaxel-evoked pain syndrome is associated with degeneration of the intraepidermal terminal arbors of primary afferent neurons, with the acti...

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Detalhes bibliográficos
Main Authors: Jin, Hai Wei, Flatters, Sarah J.L., Xiao, Wen Hua, Mulhern, Howard L., Bennett, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323600/
https://ncbi.nlm.nih.gov/pubmed/18078936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2007.11.001
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