Synthesis and characterization of mannosylated pegylated polyethylenimine as a carrier for siRNA

Regulation of gene expression using small interfering RNA (siRNA) is a promising strategy for research and treatment of numerous diseases. In this study, we develop and characterize a delivery system for siRNA composed of polyethylenimine (PEI), polyethylene glycol (PEG), and mannose (Man). Cationic...

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Autores principales: Kim, NaJung, Jiang, Dahai, Jacobi, Ashley, Lennox, Kim A., Rose, Scott, Behlke, Mark A., Salem, Aliasger K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237934/
https://ncbi.nlm.nih.gov/pubmed/21864664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2011.08.014
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